Steroid hormones often circulate in the blood as inactive sulfated forms, such as estrone sulfate and dehydroepiandrosterone sulfate. The enzyme steroid sulfatase (STS) converts these steroids into active forms, mainly estrogens, in peripheral tissues. We have previously characterized STS activity in human and mouse breast and bone tissues, and we have shown that STS can …
Cancer immunotherapies have been approved as standard second-line or in some cases even as first-line treatment for a wide range of cancers. However, immunotherapy has not shown clinically relevant success in glioblastoma (GBM). This is principally due to the brain’s “immune-privileged” status and the peculiar tumor microenvironment (TME) of GBM characterized by a lack of …
The occurrence and species/genotypes of Cryptosporidium and Giardia duodenalis infecting young livestock in selected districts of Tigray, Ethiopia were investigated, along with risks associated with infection. A total of 757 faecal samples were collected from calves, lambs, and goat kids from four rural districts in Tigray, and also from calves in periurban Mekelle, Tigray’s main city, and analysed for Cryptosporidium oocysts and Giardia cysts. Farmers …
This protocol was developed by Cepheid Medical/Scientific Affairs, to provide assistance to customers who are performing verification studies of the Xpert Xpress SARS-CoV-2/Flu/RSV test, thereby referred to as Xpress SARS CoV2-/Flu/RSV. It concerns one aspect of the verification process, which is the testing of known positive and negative samples. It is the laboratory director’s responsibility …
Aim Anthropogenic local weather change is predicted to end in the full loss of glaciers from the excessive mountains of tropical Africa, with profound impacts on the hydrology and ecology of distinctive tropical cold-water lakes positioned downstream from them. This research examines the biodiversity of Chironomidae (Insecta: Diptera) communities in these scarce Afroalpine lake methods, to …
Zaldivar-Riverón, A., Areekul, B., Shaw, M. R. & Quicke, D. L. J. (2004). Comparative morphology of the venom apparatus in the braconid wasp subfamily Rogadinae (Insecta, Hymenoptera, Braconidae) and related taxa. –Zoologica Scripta, 33, 223-237. The morphology of the venom apparatus intima in representatives of 38 genera of the problematic braconid wasp subfamily Rogadinae and different …
Neuropeptides are among the many structurally most various signaling molecules and take part in intercellular info switch from neurotransmission to intrinsic or extrinsic neuromodulation. Many of the peptidergic methods have a really historical origin that may be traced again to the early evolution of the Metazoa. In latest years, new insights into the evolution of …
Evolution of Neuropeptide Precursors in Polyneoptera (Insecta). Read More »
